Anti-Factor H binding protein from N. meningitidis mAbs

Cat. No.

MABL-1547

Name

Anti-Factor H binding   protein from N. meningitidis mAbs

Clone No.

AFD- JAR5

From

Recombinant Antibody

Isotype

Engineer antibody

Application

Blocking, WB, ELISA

Species Reactivity

Neisseria meningitidis

Basic Information

Specificity

This antibody binds to FHbp with a Kd of 54 pM.

Alternative Name

FHbp

UniProt

C6KHT4

Immunogen

Genome-derived neisserial Antigen 1870.

Application Notes

This antibody binds to N. meningitidis FHbp,   a virulence factor critical for surviving of the bacteria in the human host.   This antibody shows strong inhibition of human FH binding.

Antibody First   Published

Welsch et al. Protective activity of   monoclonal antibodies to genome-derived neisserial antigen 1870, a Neisseria   meningitidis candidate vaccine. Journal of Immunology 2004; 172(9):5606-5615   PMID:15100304

Note on publication

Describes the generation of several   antibodies against eneisserial antigen 1870 and study of their passive   protection against bacteremia.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.