Key features and details | |
Cat. No. | MABL-3546 |
Name | Anti-GM-CSF mAbs [GCC21](MABL-3546) |
Clone No. | GCC21 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Biacore, NTRL, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds to human GM-CSF at a site distinct to clone GCA43. |
Alternative Name | GMCSF; granulocyte–macrophage colony-stimulating factor; CSF2 |
UniProt | P04141 |
Immunogen | Antibody generated by sequencing of memory B-cells obtained from human patients suffering from chronic autoimmune pulmonary alveolar proteinosis. |
Application Notes | This antibody binds to human GM-CSF and has neutralizing activity. |
Antibody First Published | Piccoli et al. Neutralization and clearance of GM-CSF by autoantibodies in pulmonary alveolar proteinosis Nat Commun. 2015 Jun 16;6:7375 PMID:26077231 |
Note on publication | Describes the generation and characterization of this antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
