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Anti-HIV-1 GP41 mAbs [HGF24](MABL-3538)

简要描述:

HIV-1 neutralising antibody, that binds to the HR-2 region within gp41 (glycoprotein 41). Binding has been mapped to the linear epitope "TNLIYTLIEESQN".

产品参数:

Cat. No.:MABL-3538

Species:Engineer

Species Reactivity:HIV-1

Type:Recombinate

Application:NTRL

详细介绍

Key features and   details


Cat. No.

MABL-3538

Name

Anti-HIV-1 GP41 mAbs [HGF24](MABL-3538)

Clone No.

HGF24

From

Recombinant Antibody

Isotype

Engineer antibody

Application

NTRL

Species Reactivity

HIV-1

Basic Information


Specificity

HIV-1 neutralising antibody, that binds to the HR-2 region within gp41 (glycoprotein 41). Binding has been mapped to the  linear epitope "TNLIYTLIEESQN".

Alternative Name

Envelope glycoprotein GP120

UniProt


Immunogen

Made by immortalizing IgG-expressing B cells from patients infected with diverse clades of HIV-1

Application Notes


Antibody First   Published

Corti et al. Analysis of memory B cell responses and isolation of novel monoclonal antibodies with   neutralizing breadth from HIV-1-infected individuals. PLoS One. 2010 Jan 20;5(1):e8805. doi: 10.1371/journal.pone.0008805. PMID:20098712

Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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