Key features and details | |
Cat. No. | MABL-3529 |
Name | Anti-SARS-CoV S glycoprotein mAbs [S223](MABL-3529) |
Clone No. | S223 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | NTRL, ELISA |
Species Reactivity | SARSCoronavirus |
Basic Information | |
Specificity | SARS-CoV-neutralizing hmAbs, binds to SARS-CoV S glycoprotein, inhibiting the binding of the glycoprotein to human ACE2. |
Alternative Name | Severe Acute Respiratory Syndrome Coronavirus GP |
UniProt | |
Immunogen | Made by immortalizing IgG-expressing B cells from recovered SARS patients. |
Application Notes | |
Antibody First Published | Rockx B, Corti D, Donaldson E, Sheahan T, Stadler K, Lanzavecchia A, Baric R. Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic Severe Acute Respiratory Syndrome CoronaVirus challenge.□ J Virol. 2008 Apr;82(7):3220-35. doi: 10.1128/JVI.02377-07. Epub 2008 Jan 16. PMID:18199635 |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |