Anti-Angiotensin II mAbs

Cat. No.

MABL-408

Name

Anti-Angiotensin II mAbs

Clone No.

AFD- KAA8

From

Recombinant Antibody

Isotype

Engineer antibody

Application

Species Reactivity

Rat, Human

Basic Information

Specificity

Alternative Name

octapeptide hormone angiotensin II; AII

UniProt

P01019

Immunogen

Angiotensin II

Application Notes

Angiotensin II is a potent regulator of   blood pressure, body fluid and electrolyte homeostasis. It acts directly on   vascular smooth muscle as a potent vasoconstrictor, affects cardiac  contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and   secrete aldosterone.

Antibody First Published

Mitchell,T.J. and Reilly,T.M. Amino acid   sequence determination of three monoclonal antibodies to angiotensin II Pept.   Res. 3 (6), 277-281 (1990) PMID 2134072

Note on publication

Describes the generation of   anti-antgiotensin II antibodies.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.