Key features and details | |
Cat. No. | MABL-409 |
Name | Anti-anionic phospholipids mAbs |
Clone No. | AFD- UK4 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for the negatively charged phospholipids (PS, PI, PG, CL). The antibody does not cross-react with neutral phospholipids (PE, PC). |
Alternative Name | |
UniProt | |
Immunogen | The original antibody was generated by fusing the peripheral blood lymphocytes of three patients with SLE with a mouse-human heteromyeloma cell line, CB-F7. |
Application Notes | The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody demonstrates lupus anticoagulant activity (Menon et al., 1997; PMID 9080299). |
Antibody First Published | Menon et al., The production, binding characteristics and sequence analysis of four human IgG monoclonal antiphospholipid antibodies. J Autoimmun. 1997 Feb;10(1) 43-57. doi 10.1006/jaut.1996.0106. PMID 9080299 |
Note on publication | The original paper describes the generation and characterization of the antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
