Key features and details | |
Cat. No. | MABL-348 |
Name | Anti-acetylcholinesterase mAbs |
Clone No. | AFD- 1G |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | BLI, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for acetylcholinesterase. |
Alternative Name | EC:3.1.1.7; AChE |
UniProt | P22303 |
Immunogen | The original antibody was generated immunizing mice with full-length recombinant human acetylcholinesterase (rHuAChE). |
Application Notes | The specificity of the antibody was confirmed by ELISA analysis (Kd = 1 nM). The binding affinity of the antibody to AChE was measured by BLI (Kd= 0.32 nM) (Dafferner et al., 2017; PMID: 28892361). |
Antibody First Published | Dafferner et al. Immunopurification of Acetylcholinesterase from Red Blood Cells for Detection of Nerve Agent Exposure Chem Res Toxicol. 2017 Oct 16; 30(10): 1897–1910. PMID:28892361 |
Note on publication | The original paper describes the generation and characterization of the original antibody. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |