Key features and details | |
Cat. No. | MABL-1574 |
Name | Anti-Ferritin mAbs |
Clone No. | AFD- F11 (HSF102) |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis. |
Alternative Name | FTMT; FTL; FTH1; Ferritin mitochondrial; B8 |
UniProt | Q8N4E7 |
Immunogen | The original antibody was generated by immunizing female Balb/c mice with ferritin extracted from human spleen cells. |
Application Notes | The binding characterization of this antibody towards human spleen ferritin was done using ELISA. This antibody was also reported to show binding affinity for protein A. Binding of this antibody to ferritin causes antigen-induced conformational changes in the antibody and reduces its affinity for protein A (PMID: 9776583). |
Antibody First Published | Bespalov et al. Preparation of single-chained antibodies to human ferritin in Escherichia coli. Mol Biol (Mosk). 1993 Mar-Apr;27(2):451-60. PMID:8487773 |
Note on publication | Describes the generation of scFv antibodies using E. coli expression system. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
