Key features and details | |
Cat. No. | MABL-1566 |
Name | Anti-Fatty acid-binding protein 4 (secreted) mAbs |
Clone No. | AFD- Fab CA33 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Blocking, crystallography |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibod binds to both human and murine Fatty acid-binding protein. |
Alternative Name | FABP4; Adipocyte Protein 2; aP2 |
UniProt | P04117 |
Immunogen | This antibody was generated by immunizising New Zealand White rabbits with a mixture containing recombinant human and mouse aP2 ( CAG33184.1 and CAJ18597.1, respectively). |
Application Notes | The antibody binds to human Fatty-acid binding protein 4, which transports lipids and retinoic acids to their receptors. Administratio of CA33 t lowered fasting blood glucose, improved systemic glucose metabolism, increased systemic insulin sensitivity, and reduced fat mass and liver steatosis in obese mouse models. |
Antibody First Published | Burak et al. Development of a therapeutic monoclonal antibody that targets secreted fatty acid–binding protein aP2 to treat type 2 diabetes Science Translational Medicine 2015; 7:319ra205 PMID:26702093 |
Note on publication | Describes the generation and characterisation of this antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
