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Anti-SARS-CoV S glycoprotein mabs [S223](MABL-3570)

简要描述:

SARS-CoV-neutralizing hmAbs, binds to SARS-CoV S glycoprotein, inhibiting the binding of the glycoprotein to human ACE2.

产品参数:

Cat. No.:MABL-3570

Species:Engineer

Species Reactivity:SARSCoronavirus

Type:Recombinate

Application:NTRL, ELISA

详细介绍

Key features and   details


Cat. No.

MABL-3570

Name

Anti-SARS-CoV S glycoprotein mabs 

Clone No.

S223

From

Recombinant Antibody

Isotype

Engineer antibody

Application

NTRL, ELISA

Species Reactivity

SARSCoronavirus

Basic Information


Specificity

SARS-CoV-neutralizing hmAbs, binds to SARS-CoV S glycoprotein, inhibiting the binding of the glycoprotein to human   ACE2.

Alternative Name

Severe Acute Respiratory Syndrome Coronavirus GP

UniProt


Immunogen

 Made by immortalizing IgG-expressing B cells   from recovered SARS patients.

Application Notes


Antibody First   Published

Rockx B, Corti D, Donaldson E, Sheahan T,   Stadler K, Lanzavecchia A, Baric R. Structural basis for potent   cross-neutralizing human monoclonal antibody protection against lethal human   and zoonotic Severe Acute Respiratory Syndrome CoronaVirus challenge. J Virol. 2008 Apr;82(7):3220-35. doi:10.1128/JVI.02377-07. Epub 2008 Jan 16. PMID:18199635

Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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