Key features and details | |
Cat. No. | MABL-373 |
Name | Anti-alpha-4 integrin mAbs |
Clone No. | AFD-21.6 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Block, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds to human alpha-4-integrin |
Alternative Name | CD49D; CD49 antigen-like family member D; Integrin alpha-IV; VLA-4subunit alpha |
UniProt | P13612 |
Immunogen | Alpha-4 integrin. |
Application Notes | This antibody binds to human alpha-4-integrin and can inhibit the binding oflymphocytes to endothelial cells, suppressing inflammation. |
Antibody First Published | Methods of inhibiting alpha-4-dependent interactions with VCAM-1 with anti-VLA-4 antibodies Patent US8246958 PMIDVLA-4 antibodies Patent US8246958 PMID |
Note on publication | Describes the use of this murine antibody and humanized counterpart, their affinities and biological function. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
