Key features and details | |
Cat. No. | MABL-2867 |
Name | Anti-saxiton mAbs |
Clone No. | AFD- 5F7 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | SPR |
Species Reactivity | Specie independent |
Basic Information | |
Specificity | The antibody is specific for STX. It cross reacts with dc-STX. STX is a potent neurotoxin and the best-known paralytic shellfish toxin. Ingestion of saxitoxin by humans, usually by consumption of shellfish contaminated by toxic algal blooms, is responsible for the illness known as paralytic shellfish poisoning. |
Alternative Name | STX; [(3aS,4R,10aS)-10,10-dihydroxy-2,6-diiminooctahydro-1H,8H- pyrrolo[1,2-c]purin-4-yl]methyl carbamate |
UniProt | |
Immunogen | The original antibody was generated by immunizing mice with STX-glucose oxidase immunogen. |
Application Notes | The binding affinity of the original format of the antibody to STX was measured by surface plasmon resonance (Kd= 2.6 nM). Further, the antibody was used for developing an anti-STX xMAP assay (Shriver-Lake et al., 2017; PMID: 27879646). |
Antibody First Published | Immunochemical Approaches to the Analysis of Paralytic Shellfish Poisoning Toxins |
Note on publication | The paper describes the generation and characterization of the antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
