Key features and details | |
Cat. No. | MABL-2886 |
Name | Anti-Serum Albumin mAbs |
Clone No. | AFD- Nb.b201 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds a convex protrusion on the surface of human serum albumin. |
Alternative Name | Human Serum Albumin; HSA; albumin |
UniProt | P02768 |
Immunogen | The original antibody was isolated from a synthetic nanobody library starting from a consensus framework derived from llama genes IGHV1S1–S5. |
Application Notes | This antibody specifically binds human serum albumin and does not cross react with mouse serum albumin. The binding specificity of this antibody towards fluorescently labeled HSA was done using flow cytometry. The binding affinity of this antibody for human serum albumin was measure by surface plasmon resonance and was found to be 430 nM |
Antibody First Published | McMahon et al. Yeast surface display platform for rapid discovery of conformationally selective nanobodies. Nat Struct Mol Biol. 2018 Mar;25(3):289-296. PMID:29434346 |
Note on publication | Describes the use of a yeast surface display platform for rapid discovery of conformationally selective nanobodies. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |