Key features and details | |
Cat. No. | MABL-2777 |
Name | Anti-PVRIG mAbs |
Clone No. | AFD- 334MXX |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FACS |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody specifically binds to human PVRIG. |
Alternative Name | Poliovirus receptor-related immunoglobulin domain-containing protein; Transmembrane protein PVRIG; CD112 receptor (CD112R) |
UniProt | Q6DKI7 |
Immunogen | The original antibody was generated by immunizing mice with human PVRIG linked to a human IgG Fc region. |
Application Notes | The original version and the humanized version antibody were able to inhibit PVRIG activity and signaling. The binding of the original format or the humanized version of the antibody to PVRIG decreased PVRL2 activity, as shown by FACS analysis on HEK-293T cells transfected with hPVRIG (WO2018017864A3). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
