Key features and details | |
Cat. No. | MABL-2712 |
Name | Anti-Podoplanin mAbs |
Clone No. | AFD- PMab292 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, FC, IHC |
Species Reactivity | Ferret (Mustela putorius furo) |
Basic Information | |
Specificity | The antibody is specific for ferret Podoplanin. Podoplanin is a type I transmembrane sialoglycoprotein that plays essential roles in the development of the heart, alveoli, and lymphatic system. |
Alternative Name | Pmab-292; PDPN; ferret PDPN; ferPDPN; ferret |
UniProt | G9KFV5 |
Immunogen | |
Application Notes | The antibody recognized ferPDPN-overexpressed Chinese hamster ovary-K1 (CHO/ferPDPN) cells by flow cytometry and Western blotting. The kinetic analysis using flow cytometry showed that the KD of the antibody for CHO/ferPDPN was 3.4 × 10-8 M. Furthermore, PMab-292 detected lung type I alveolar epithelial cells, lymphatic endothelial cells, and glomerular/Bowman's capsule in the kidney using immunohistochemistry (Goto et al., 2022; PMID: 35471053). |
Antibody First Published | Goto et al. Development of a Monoclonal Antibody PMab-292 Against Ferret Podoplanin Monoclon Antib Immunodiagn Immunother. 2022 Apr;41(2):101-109. PMID:35471053 |
Note on publication | The original paper describes the generation and characterization of the antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
