Key features and details | |
Cat. No. | MABL-2076 |
Name | Anti-IL-4 mAbs |
Clone No. | AFD- 12-6-68 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human IL-4. Interleukin-4 is a cytokine secreted primarily by mast cells, T- cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. It induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. It also induces expression of class II MHC molecules on resting B-cells and enhances both secretion and cell surface expression of IgE and IgG1. |
Alternative Name | IL4; BSF-1; Interleukin-4; B-cell stimulatory factor 1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra |
UniProt | P05112 |
Immunogen | The original antibody was generated by immunizing BALB/c mice subcutaneously with 25 µg of human IL-4 in 100 µl of 150 mM sodium chloride emulsified with 100 µl of complete Freund’s adjuvant. |
Application Notes | The binding of this antibody to human IL-4 was confirmed with ELISA (PMID: 12825686). |
Antibody First Published | Ehsani et al. Expression of anti human IL-4 and IL-6 scFvs in transgenic tobacco plants. Plant Mol Biol. 2003 May;52(1):17-29. PMID:12825686 |
Note on publication | Describes the expression of two murine antibodies in Agrobacterium tumefaciens. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
