Key features and details | |
Cat. No. | MABL-2075 |
Name | Anti-IL-4 mAbs |
Clone No. | AFD- 11B11 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | in vivo, ELISA, FC, IHC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | Binds to a core functional region of murine IL-4, which prevents this cytokine from interacting with its cognate receptor (Yao et al., 2006 PMID: 16361318). |
Alternative Name | Interleukin-4; Il4; Il-4; B-cell IgG differentiation factor; B-cell growth factor 1; B-cell stimulatory factor 1; BSF-1 |
UniProt | P07750 |
Immunogen | BSF-1 / IL-4 purified from serum-free supernatants of cultured EL-4 cells (a C57BL/6 thymoma) induced with 4β-phorbol 12β-myristate 12α-acetate for 48h. |
Application Notes | |
Antibody First Published | Ohara J, Paul WE. Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1. Nature. 1985 May 23-29;315(6017):333-6. PMID:2582266 |
Note on publication | Describes the isolation of the monclonal antibody and its use in studying IL-4 (before it was named IL-4). |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
