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Anti-Estradiol mAbs

简要描述:

This antibody is specific for estradiol. Estradiol is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles.

产品参数:

Cat. No.:MABL-1522

Species:Engineer

Species Reactivity:Species independent

Type:Recombinate

Application:RIA

详细介绍

Key features and   details


Cat. No.

MABL-1522

Name

Anti-Estradiol mAbs

Clone No.

AFD- 15H11

From

Recombinant Antibody

Isotype

Engineer antibody

Application

RIA

Species Reactivity

Species independent

Basic Information


Specificity

This antibody is specific for estradiol.   Estradiol is an estrogen steroid hormone and the major female sex hormone. It   is involved in the regulation of the estrous and menstrual female   reproductive cycles.

Alternative Name

7-(O-carboxymethyl)oximinoestradiol;   17β-estradiol; oestradiol

UniProt


Immunogen

This antibody was raised by immunizing male   Balb/c mice with 7-(O- carboxymethyl)oximinoestradiol-BSA.

Application Notes

A radioimmunoassay was preformed with the   mouse version of this antibody on estradiol tracers (Rousselot et al, 1997;   pmid:9201930).

Antibody First   Published

Rousselot et al. Specific photoaffinity   labeling of Tyr-49 on the light chain in the steroid-combining site of a   mouse monoclonal anti-estradiol antibody using two epimeric 6alpha- and   6beta-(5-azido-2-nitrobenzoyl)amidoestradiol photoreagents. Biochemistry.   1997 Jun 24;36(25):7860-8. PMID:9201930

Note on publication

A mouse monoclonal   anti-7-(O-carboxymethyl)oximinoestradiol antibody was photoaffinity labeled   with two cross-reactive 6alpha- and   6beta-(5-azido-2-nitrobenzoyl)amido[17alpha- 3H]estradiol photoreagents   (6alpha- and 6beta-ANBA-[17alpha-3H]estradiol).

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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