Cat. No.
MABL-820
Application
IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
9D11B6E6
From
Recombinant Antibody
Specificity
The antibody is specific for CD23. CD23 is a low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. It has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Alternative Names
CGMCC No. 19689; Low affinity immunoglobulin epsilon Fc receptor; BLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; SP23; FcεRII
UniProt
P06734
Immunogen
The original antibody was generated by immunizing mice with CD23.
Application Notes
The antibody 9D11B6E6 and the commercial antibody SP23 were used to stain B-cell lymphoma. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 9D11B6E6 was higher than the commercial antibody. The antibody and the commercially available antibody SP23 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN112442124B).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
