Cat. No.
MABL-763
Application
Blocking, IP, SPR, FC, IF, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
HD37
From
Recombinant Antibody
Specificity
This antibody is specific for human CD19, a 95 kDa protein expressed in the B-lymphocyte lineage.
Alternative Names
Leu12; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19 T-cell surface antigen Leu-12; CD19
UniProt
P15391
Immunogen
Cells from a hairy cell leukemia patient.
Application Notes
This antibody binds to CD19 and is able to inhibit B-cell activation (Pezutto 1987). This antibody was measured to have a KD of 4.1 ± 0.3 nM against human CD19 and did not compete with clone FMC63 (available as Ab00613) (Sakemura et al., 2023; PMID: 37879074).
Antibody First Published
Pezzutto et al. HD37 Monoclonal Antibody: A Useful Reagent for Further Characterization of “Non-T, Non-B” Lymphoid Malignancies Leukocyte Typing II, pp 391-402, 1986, ISBN 978-1-4612-4848-4, DOI 10.1007/978-1-4612-4848-4_33.
Note on publication
Describes the generation and characterization of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
