Cat. No.
MABL-384
Application
ELISA, FC
Isotype
Engineer antibody
Species Reactivity
Species independent
Clone No.
m86
From
Recombinant Antibody
Specificity
This antibody binds to the alpha-gal epitope on glycoproteins and glycolipids.
Alternative Names
A-Gal; Gal-alpha-1 – 3Gal-beta-1 – 4GlcNAc-R
UniProt
Immunogen
Rabbit red cells, on which α-gal is the major carbohydrate epitope, were injected into alpha 1,3 galactosyltransferase knock-out mice.
Application Notes
This antibody binds to the alpha-gal epitope found on many glycoproteins and glycolipids of non-primate mammalis, prosimians and New World monkeys. Antibodies agains the alpha-gal epitopes occur naturally in Old World monkeys, apes and humans, and induce xenograft rejection from nonprimate animals.
Antibody First Published
Chen, Radic and Galili Genes coding evolutionary novel anti-carbohydrate antibodies studies on anti-Gal production in alpha 1,3 galactosyltransferase knock out mice. Mol Immunol.2000 Jun;37(8)：455-66. PMID：11090880
Note on publication
Describes the generation and characterization of anti-gal epitope antibodies raised in alpha 1,3 galactosyltransferase knock-out mice.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
