Cat. No.
MABL-373
Application
Block, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
21.6
From
Recombinant Antibody
Specificity
This antibody binds to human alpha-4-integrin
Alternative Names
CD49D; CD49 antigen-like family member D; Integrin alpha-IV; VLA-4subunit alpha
UniProt
P13612
Immunogen
Alpha-4 integrin.
Application Notes
This antibody binds to human alpha-4-integrin and can inhibit the binding oflymphocytes to endothelial cells, suppressing inflammation.
Antibody First Published
Methods of inhibiting alpha-4-dependent interactions with VCAM-1 with anti-VLA-4 antibodies Patent US8246958 PMIDVLA-4 antibodies Patent US8246958 PMID
Note on publication
Describes the use of this murine antibody and humanized counterpart, their affinities and biological function.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
