Cat. No.
MABL-359
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
E. coli, Salmonella enterica
Clone No.
Fab21
From
Recombinant Antibody
Specificity
Binds to the AdiC transporter of various enteric bacteria, including E.coli and S. enterica.
Alternative Names
Arginine: Agmantine Antiporter
UniProt
P60061
Immunogen
E.coli AdiC.
Application Notes
This antibody binds to AdiC of enteric bacteria. AdiC is a membrane protein acting as a transporter that imports arginine from the gastric juice and exports its decarboxylation product agmatine along with protons. AdiC is responsible for the acid-resistance of enteric bacteria. The antibody does not inhibit function of the transporter.
Antibody First Published
Fang et al. Structure of a prokaryotic virtual proton pump at 3.2 A resolution. Nature 2009; 460(7258):1040-1043 PMID:19578361
Note on publication
Describes the crystallisation of AdiC, an L-arginine transporter, with the aid of an AdiC-binding Fab.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
