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Anti-Arl13b mAbs

简要描述:

This antibody was specific for Arl13b. It does not cross-react with Arl13a. Arl13b is a cilium- specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B.

产品参数:

Cat. No.:MABL-204

Species:Engineer

Species Reactivity:Rat,Mouse

Type:Recombinate

Application:ICC, WB, IF, IHC

详细介绍

Key features and details

Cat. No.

MABL-204

Name

Anti-Arl13b mAbs

Clone No.

AFD-N295B/66R

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ICC, WB, IF, IHC

Species Reactivity

Rat, Mouse

Basic Information

Specificity

This antibody was specific for   Arl13b. It does not cross-react with Arl13a. Arl13b is a cilium- specific  protein required to control the microtubule-based, ciliary axoneme structure.   May act by maintaining the association between IFT subcomplexes A and B.

Alternative Name

ADP-ribosylation factor-like protein 13B;   ADP-ribosylation factor-like protein 2-like 1; ARL2-like protein 1; N295B/66

UniProt

Q3SXY8

Immunogen

This antibody was raised against a fusion   protein of amino acids 208-427 of mouse Arl13b.

Application Notes

Rat E11.5 embryonic spinal cords   were used for immunofluorescence with this antibody (Ferent et al, 2019;   PMID:31825820). Immunoblotting was preformed on lysated mouse tissue using   this antibody (Gigante et al, 2020; PMID:32129762). Arl13bhnn MEFs were immunostained   with this antibody (Revenkova et al, 2018; PMID:29592971). Immunofluorescence   was preformed on mouse kidney cells using this antibody (Hwang et al, 2019;   PMID:30799239). Immunohistochemistry was preformed against mouse embryos   using this antibody (Fiore et al, 2020; PMID:32169553). X. tropicalis tissues were immunostained with this antibody (Saurabh et al, 2018; PMID:30377171).   Immunocytochemistry was preformed on MEFs with this antibody (Muñoz-Estrada   et al, 2019; PMID:31391239). This antibody was used for immunohistochemistry   on mouse tissues (Seungshin et al, 2016; PMID:27261005).

Antibody First Published

Seungshin et al. Mutations in Dnaaf1   and Lrrc48 Cause Hydrocephalus, Laterality Defects, and Sinusitis in Mice G3   (Bethesda). 2016 Aug 9;6(8):2479-87. PMID:27261005

Note on publication

Decribes the use of this antibody in an immunohistochemistry   experiment.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.


 


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