Anti-ZNF423 mAbs

Cat. No.

MABL-203

Name

Anti-ZNF423 mAbs

Clone No.

AFD-N328B/37R

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ICC, WB, IHC

Species Reactivity

Human, Mouse

Basic Information

Specificity

This antibody is specific for ZNF423. The antibody does not cross-react   with ZNF521. ZNF423 is a transcription factor that can both act as an   activator or a repressor depending on the context. Plays a central role in   BMP signaling and olfactory neurogenesis.

Alternative Name

Zinc finger protein 423; Olf1/EBF-associated   zinc finger protein; hOAZ; Smad- and Olf-interacting zinc finger protein;   N328B/37

UniProt

Q2M1K9

Immunogen

This antibody was raised against a fusion   protein of amino acids 1-180 of human ZNF423

Application Notes

This antibody is recommended for detection and analysis of ZNF423 by   immunocytochemistry, immunohistochemistry or western blot. For instance, the   mouse version of this antibody was used to detect ZNF423 by western blot in s   crude low-speed pellet fractions from adult rat brain and neonate wild-type   (WT) and nur12 (ZNF423 knockout or KO) mouse cerebella. Furthermore it was   used to detect ZNF423 by immunocytochemistry in embryonic wild-type (WT) and   nur12 (ZNF423 knockout) mouse cerebella.

Antibody First Published

Andrews et al. A toolbox of IgG   subclass-switched recombinant monoclonal antibodies for enhanced multiplex   immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360

Note on publication

Describes the generation of a library of recombinant monoclonal   antibodies (R- mAbs) from a pool of mAb-producing hybridomas for neuroscience   research.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.