Key features and details | |
Cat. No. | MABL-113 |
Name | Anti-LRRTM4 mAbs |
Clone No. | AFD-N205B/22 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ICC, IP, WB, IF |
Species Reactivity | Rat, Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for the LRRTM4 protein, but it binds to both the short and long isoforms of the protein. LRRTM4 may play a role in the development and maintenance of the vertebrate nervous system. |
Alternative Name | N205B/22R; Leucine-rich repeat transmembrane neuronal protein 4 |
UniProt | Q86VH4 |
Immunogen | This antibody was raised by immunising BALB/c mice with a synthetic peptide amino acids 470-484 (ARESERQMNSPLQEY, cytoplasmic C-terminus) of human LRRTM4. |
Application Notes | This antibody was used to preform an immunopercipitation on lysate from mouse retinas (Sinha et al, 2020; PMID:31974009). Western blot was preformed on proteins from mouse retinas using this antibody (Sinha et al, 2020; PMID:31974009). This antibody was used for immunocytochemistry on mouse neurons (de Wit et al, 2013; PMID:23911103). Immunofluorescense was preformed on the eyecups and lenses of C57BL mice using this antibody (Agosto and Wensel, 2020; PMID:32390181). |
Antibody First Published | de Wit et al. Unbiased discovery of glypican as a receptor for LRRTM4 in regulating excitatory synapse development Neuron. 2013 Aug 21;79(4):696-711. PMID:23911103 |
Note on publication | This article describes research on the ligand-receptor interactions of the LRRTM4 protein |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
