Key features and details | |
Cat. No. | MABL-081 |
Name | Anti-Kv2.1 K+ Channel mAbs |
Clone No. | AFD-K89/34 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IB, IP, IHC |
Species Reactivity | Rat, Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for Kv2.1. It does not cross-react with rat Kv2.2. |
Alternative Name | K89/34R; Potassium voltage-gated channel subfamily B member 1; Delayed rectifier potassium channel 1; DRK1; Kcnb1; Shab |
UniProt | P15387 |
Immunogen | This antibody was raised by immunising BALB/c mice with a synthetic peptide consisting of the cytoplasmicC-terminus (amino acids 837-853) of rat Kv2.1 |
Application Notes | This antibody has been used in immunoblot analysis of membranes prepared from adult rat (Misonou et al, 2006) and mouse brain, and from human hippocampus, cerebral cortex and cerebellum (Andrews et al, 2019; PMID:30667360). It has also been used in immunohistochemical analysis of adult rat brain (Misonou et al, 2006) and hippocampus sections (Andrews et al, 2019; PMID:30667360). |
Antibody First Published | Misonou et al. Bidirectional Activity-Dependent Regulation of Neuronal Ion Channel Phosphorylation Journal of Neuroscience 27 December 2006, 26 (52) 13505-13514; PMID:17192433 |
Note on publication | Describes the original use of this antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
