Key features and details | |
Cat. No. | MABL-082 |
Name | Anti-WAVE-1 mAbs |
Clone No. | AFD-K91/36 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IB, IP, IHC |
Species Reactivity | Rat, Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for WAVE-1. |
Alternative Name | K91/36R; Wiskott-Aldrich syndrome protein family member 1; WAVE1; WASP family protein member 1; Verprolin homology domain-containing protein 1; KIAA0269; WASF1; SCAR1; SCAR |
UniProt | Q92558 |
Immunogen | This antibody was raised by immunising BALB/c mice with a synthetic peptide corresponding to amino acids 477-498 of human WAVE-1. |
Application Notes | This antibody has been used in immunoblot analysis of membranes prepared from adult rat and mouse brain, and from human hippocampus and cerebral cortex (Andrews et al, 2019; PMID:30667360). It has also been used in immunohistochemical analysis of adult rat whole brain and hippocampus sections (Andrews et al, 2019; PMID:30667360). Additionally, in the analysis of adult mouse brain lysates, this antibody has been used for WAVE1 immunoprecipitation (Chen et al, 2014) and WAVE1 western blot (Chia et al, 2014). |
Antibody First Published | Chen et al. The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton Cell. 2014 Jan 16;156(1-2):195-207. PMID:24439376 |
Note on publication | Describes the original use of this antibody. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |