Cat. No.
MABL-3687
Application
FC, IHC, IHC-Fr
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
YNB46.1.8 (Campath-9H)
From
Recombinant Antibody
Specificity
Recognizes the 55kDa human CD4 cell surface antigen, expressed by helper T lymphocytes and by monocytes.
Alternative Names
Leu-3/T4; Cluster of differentiation 4; T-cell surface glycoprotein CD4; T- cell surface antigen T4/Leu-3
UniProt
P01730
Immunogen
Rat T-cell line (NB2) transfected with the human CD4.
Application Notes
Antibody First Published
Mathieson PW1, Cobbold SP, Hale G, Clark MR, Oliveira DB, Lockwood CM, Waldmann H. Monoclonal-antibody therapy in systemic vasculitis. N Engl J Med. 1990 Jul 26;323(4):250-4. PMID:2366834
Note on publication
Describes the production of the clone YNB46.1.8 and explores its therapeutic potential as a combinatorial agent with Campath 1-H for the treatment of intractable systemic vasculitis
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
