Anti-Avian influenza virus nucleoprotein mAbs

Cat. No.

MABL-466

Name

Anti-Avian influenza virus nucleoprotein mAbs

Clone No.

From

Isotype

Application

in vivo, ELISA

Species Reactivity

Avian influenza virus

Basic Information

Specificity

This antibody is specific for the avian influenza virus nucleoprotein.

Alternative Name

Nucleocapsid protein

UniProt

P26056

Immunogen

The original antibody was generated by immunizing alpacas with avian influenza virus nucleoprotein, creating the appropriate phage display library, and panning against the original target.

Application Notes

The binding specificity of the original   camelid (alpaca) single-domain antibody (sdAb; VHH) was tested in an ELISA.   This antibody was used to generate an anti-avian influenza nucleoprotein and   anti-human IgA bi-specific construct together with Ab04649 [A8]. The   bi-specific construct detected a range of influenza virus strains in ELISA,   including low-virulence and vaccine strains. Namely, H1N1, H3N2, H5N3, H5N1   (LP), H7N3(LP), H8N4, H10N8, H11N6, H12N5, H2N2, H4N6, H5N9, H6N2, H7N7, H9N2, H10N7,H12N6, and H13N6. The bi-specific construct also exhibited a significantly prolonged stability in vivo in Balb/c mice compared to the sdAb version of the antibody (CN111116752B).

Antibody First Published

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.