Anti-Anti-platelet aggregation protein mAbs

Cat. No.

MABL-415

Name

Anti-Anti-platelet aggregation protein mAbs

Clone No.

AFD- 8H7

From

Recombinant Antibody

Isotype

Engineer antibody

Application

Blocking, ELISA

Species Reactivity

Anopheles stephensi

Basic Information

Specificity

This antibody binds specifically to the turn-region of AAPP.

Alternative Name

Ansg-1; AAPP

UniProt

Q7YT37

Immunogen

Recombinant AAPP.

Application Notes

This antibody binds specifically to   Anopheles anti-platetelet protein (AAPP), which blocks platelet adhesion to   collagen by binding directly to collagen and subsequently aggregating   platelets. This antibody prevents AAPP binding to collagen.

Antibody First Published

Sugiyama et al. The crystal  strucuture of the active doain of Anopheles anti-platelet protein, a powerful   anti-coagulant, in complex with an antibody. Journal of Biological CHemistry   2015; 289(23):16303-16312 PMID:24764297

Note on publication

Describes the generation of an anti-   anti-platelet protein antibody and subsequent crystallography.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.