Key features and details | |
Cat. No. | MABL-387 |
Name | Anti-alpha-Latrotoxin mAbs |
Clone No. | AFD- TPL0020_02_G9 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Latrodectus tredecimguttatus (Mediterranean black widow spider) |
Basic Information | |
Specificity | TPL0029_02_G9 antibody recognizes alpha-Latrotoxin from the venom of Latrodectus tredecimguttatus (Mediterranean black widow spider). |
Alternative Name | α-latrotoxin; Alpha-latrotoxin-Lt1a; Alpha-LTX-Lt1a; Alpha-LTX;latrotoxin; Latrodectus mactans tredecimguttatus |
UniProt | P23631 |
Immunogen | Single chain variable fragment (scFv)-displaying phages from the IONTAS phage library λ with a phage diversity of 1.6・10^10 were used to select scFvs, which bind biotinylated α-latrotoxin from the Mediterranean black widow spider (L. tredecimguttatus). Three rounds of selections were performed to enrich the pool of phages with high affinity to the toxin. |
Application Notes | TPL0029_02_G9 antibody was demonstrated to have high affinity towards the alpha-Latrotoxin from the venom of Latrodectus tredecimguttatus (Mediterranean black widow spider) via ELISA.This antibody is recommended for the research on the antitoxin against Latrodectus tredecimguttatus spider bites. |
Antibody First Published | Føns et al. Discovery of human antibody fragments against spider venom toxins. 10.13140/RG.2.2.21155.71202. PMID |
Note on publication | This poster describes the generation and characterization of the TPL0029_02_G9 antibody, as a potential treatment for Latrodectus tredecimguttatus spider bites. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
