Key features and details | |
Cat. No. | MABL-360 |
Name | Anti-Advanced Glycation End Products (AGE), Methylgloxal (MG) mAbs |
Clone No. | AFD- 3D11 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA, IHC |
Species Reactivity | Rat, Human, Mouse |
Basic Information | |
Specificity | This antibody recognises methylglyoxal (MG) and is specific to MG-modified proteins, lipids and nucleic acids. 3D11 does not cross-react with CML, CEL, or other AGE epitopes. |
Alternative Name | Methylglyoxal; MG; AGE; pyruvaldehyde; 2-oxopropanal; AGEs; MG3D11 |
UniProt | |
Immunogen | This antibody was raised by immunising BALB/c mice with MG-modified ovalbumin. |
Application Notes | 3D11 antibody is recommended for the identification of methylglyoxal (MG) from various sources, such as foods, serum, tissues, cells and others, in order to evaluate the concentration of AGEs. ELISA with this antibody has been established as a very effective method in the assessment of the amount of AGE - methylglyoxal in various tissue and food samples (Cai et al., 2012; Vlassara et al., 2002). |
Antibody First Published | Cai et al. Oxidative stress-inducing carbonyl compounds from common foods novel mediators of cellular dysfunction. Mol Med. 2002 Jul;8(7): 337-46. PMID:12393931 |
Note on publication | This article describes the generation and characterisation of 3D11 antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
