Key features and details | |
Cat. No. | MABL-3047 |
Name | Anti-Tetraspanin 1 mAbs |
Clone No. | AFD- 4/12 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA, IF, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for the largest extracellular domain of tetraspanin 1. |
Alternative Name | Net1; C4.8; Tetraspanin-1; Tspan-1; TSPAN1; Tetraspan NET-1; Tetraspanin TM4-C; TM4SF |
UniProt | O60635 |
Immunogen | This antibody was raised by immunising BALB/c mice with the major extracellular domain of tetraspanin 1. |
Application Notes | The specificity of this antibody for tetraspanin 1 has been confirmed in ELISA analysis (Hölters et al, 2013). This antibody has been used in immunohistochemical analysis of tetraspanin 1 expression in paraffin-embedded sections of normal and cancerous cervical tissue arrays (Hölters et al, 2013), and in frozen tissue samples. This antibody has also been used for immunocytochemical staining for tetraspanin 1 expression, in SiHa cells following adenoviral transduction (Hölters et al, 2013). |
Antibody First Published | Hölters et al. Tetraspanin 1 promotes invasiveness of cervical cancer cells Int J Oncol. 2013 Aug;43(2):503-12. PMID:23754316 |
Note on publication | Describes the original generation of this antibody, and its use in immunohistochemical analysis. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
