Key features and details | |
Cat. No. | MABL-2909 |
Name | Anti-Siglec-7 mAbs |
Clone No. | AFD- Siglec7-01 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human siglec-7. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. |
Alternative Name | CD328; SIGLEC7; AIRM1; AIRM-1; SIGL7; CDw328; D-siglec; p75; Sialic acid-binding Ig-like lectin 7; Adhesion inhibitory receptor molecule 1; QA79 membrane protein |
UniProt | Q9Y286 |
Immunogen | The original antibody was isolated from a human Fab antibody library by panning against human siglec-7. |
Application Notes | This antibody can bind recombinant human siglec-7 protein in an ELISA and western blot. The binding affinity of the IgG antibody for human siglec-7 was reported to be Kd= 71.5 nM. In vitro, this antibody was capable of enhancing killing effect of NK cells on tumor cells (CN106831989). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
