Key features and details | |
Cat. No. | MABL-2907 |
Name | Anti-Siderocalin mAbs |
Clone No. | AFD- MAB1857 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | crystalisation, WB, ELISA |
Species Reactivity | Mouse |
Basic Information | |
Specificity | Detects recombinant mouse (rm)Lipocalin-2 and does not cross-react with rhLipocalin-1 or rhLipocalin‑2 by ELISA or WB. |
Alternative Name | 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; HNL; LCN2; lipocalin 2 (oncogene 24p3); lipocalin 2; Lipocalin-2; migration-stimulating factor inhibitor; MSFI; neutrophil gelatinase-associated lipocalin; NGAL; NGALlipocalin-2; Oncogene 24p3; p25; Siderocalin; 228418 |
UniProt | P11672 |
Immunogen | Recombinant mouse Lipocalin2/NGAL - Gln21Asn200. |
Application Notes | This antibody binds to mouse siderocalin, can be used for western blots and, as an Fab fragment, has been co-crystallized with murine Scn. It is unclear whether or not the antibody is able to block the interaction between Scn and cell-surface receptors mediating endocytosis and subsequent apoptosis (Correnti et al. 2012). |
Antibody First Published | Nairz M et al. 2008 Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium Eur J Immunol. 2008 Jul;38(7):1923-36. doi: 10.1002/eji.200738056. PMID:18581323 |
Note on publication | Describes how this antibody was used to detect siderocalin via immunoblotting. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
