Key features and details | |
Cat. No. | MABL-2901 |
Name | Anti-Shiga-toxin 2 mAbs |
Clone No. | AFD- S2C6 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Escherichia phage 933W (Bacteriophage 933W) |
Basic Information | |
Specificity | This antibody binds the A subunit of Shiga-like toxin 2. Stx2 is a toxin produced by Shiga toxin (Stx)-producing E. coli (STEC) strains. Infections with STEC can lead to diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome (HUS). |
Alternative Name | SLT2; stxA2; stxII; stx2A; SLT-2 A subunit; SLT-2a; SLT-IIa; Shiga-like toxin 2 subunit A; Verocytotoxin 2 subunit A; Verotoxin 2 subunit A; rRNA N-glycosidase 2 |
UniProt | P09385 |
Immunogen | The original antibody was generated by immunizing BALB/c mice with StxII protein mixed with an equal volume of Freund’s complete adjuvant. |
Application Notes | This antibody can be used as a detection antibody in the detection of shiga like toxin 2 subunit A in a sample using double antibody sandwich ELISA. The capture can be done using S2D8 antibody (Shi et al, 2016; CN103235140). |
Antibody First Published | Shi et al. Establishment of a double-antibody sandwich ELISA for the detection of shiga toxin typeⅡin shiga toxin-producing Escherichia coli infection. Chinese Journal of Microbiology and Immunology 2016;36(10):771-774 |
Note on publication | Describes a double-antibody sandwich ELISA method for detection of shiga toxin typeⅡ ( StxⅡ) using two antibodies S2C6 and S2D8. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
