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Anti-Shiga-toxin 2 mAbs

简要描述:

This antibody binds the A subunit of Shiga-like toxin 2. Stx2 is a toxin produced by Shiga toxin (Stx)-producing E. coli (STEC) strains. Infections with STEC can lead to diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome (HUS).

产品参数:

Cat. No.:MABL-2901

Species:Engineer

Species Reactivity:Escherichia phage 933W (Bacteriophage 933W)

Type:Recombinate

Application:ELISA

详细介绍

Key features and   details


Cat. No.

MABL-2901

Name

Anti-Shiga-toxin 2 mAbs

Clone No.

AFD- S2C6

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ELISA

Species Reactivity

Escherichia phage 933W (Bacteriophage 933W)

Basic Information


Specificity

This antibody binds the A subunit of Shiga-like   toxin 2. Stx2 is a toxin produced by Shiga toxin (Stx)-producing E. coli   (STEC) strains. Infections with STEC can lead to diarrhea, hemorrhagic   colitis, and hemolytic uremic syndrome (HUS).

Alternative Name

SLT2; stxA2; stxII; stx2A; SLT-2 A subunit;   SLT-2a; SLT-IIa; Shiga-like toxin 2 subunit A; Verocytotoxin 2 subunit A;   Verotoxin 2 subunit A; rRNA N-glycosidase 2

UniProt

P09385

Immunogen

The original antibody was generated by immunizing   BALB/c mice with StxII protein mixed with an equal volume of Freund’s   complete adjuvant.

Application Notes

This antibody can be used as a detection antibody in the detection of shiga like toxin 2 subunit A in a sample using  double antibody sandwich ELISA. The capture can be done using S2D8 antibody   (Shi et al, 2016; CN103235140).

Antibody First   Published

Shi et al. Establishment of a   double-antibody sandwich ELISA for the detection of shiga toxin typeⅡin shiga   toxin-producing Escherichia coli infection. Chinese Journal of Microbiology   and Immunology 2016;36(10):771-774

Note on publication

Describes a double-antibody sandwich ELISA   method for detection of shiga toxin type ( Stx) using two antibodies S2C6 and S2D8.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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