Key features and details | |
Cat. No. | MABL-2801 |
Name | Anti-RANK-L mAbs |
Clone No. | AFD- RL |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Blocking, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for human-RANK-L. RANKL is a tumor necrosis factor (TNF)-related protein that binds to, and activates, the TNF receptor (TNFR)-related protein Receptor Activator of NF-kB (RANK). RANKL acts as the key cytokine that regulates osteoclast differentiation and activation during normal bone remodeling and during disease. |
Alternative Name | CD254; TRANCE; RANKL; ODF; OPGL; Tumor necrosis factor ligand superfamily member 11; Osteoclast differentiation factor; Osteoprotegerin ligand; Receptor activator of nuclear factor kappa-B ligand; TNF-related activation-induced cytokine |
UniProt | O14788 |
Immunogen | The original antibody was generated by panning a Fab library against RANKL. |
Application Notes | The origina antibody was capable of blocking the interactions between RANKL and its receptor RANK. The original antibody could potentially be used in an ELISA analysis (WO2015030701A1) |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
