Key features and details | |
Cat. No. | MABL-2765 |
Name | Anti-Protocadherin 30 mAbs |
Clone No. | AFD- 8C5 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC, IF, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody recognizes protocadherin FAT2 which is involved in the regulation of cell migration. |
Alternative Name | Protocadherin Fat 2; FAT 2; hFat2; Cadherin family member 8; Multiple epidermal growth factor-like domains protein 1; Multiple EGF-like domains protein 1; Fat 2 |
UniProt | Q9NYQ8 |
Immunogen | The original mouse IgG1 version of this antibody was raised by immunizing mice with a purified recombinant human FAT2 fusion protein. |
Application Notes | This antibody is recommended for the detection and analysis of protocadherin FAT2. It was used to detect and visualize protocadherin FAT2 via immunohistochemistry in formalin fixed, paraffin- embedded tissues, such as human urothelial cancer and human cervical carcinoma. |
Antibody First Published | Chen and Gumbiner Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity J Cell Biol. 2006 Jul 17;174(2);301-13. doi: 10.1083/jcb.200602062. PMID:16847104 |
Note on publication | This article describes the anti-protocadherin antibody. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |