Key features and details | |
Cat. No. | MABL-2757 |
Name | Anti-Progesterone Receptor mAbs |
Clone No. | AFD- 14B3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for PR protein. PR is a protein molecule, a cellular core receptor belonging to a steroidal superfamily, which can be bonded to the corresponding hormone to form a hormone-receptor complex, enabling hormones to exert their biological effects. |
Alternative Name | PR; Nuclear receptor subfamily 3 group C member 3 |
UniProt | P06401 |
Immunogen | The original antibody was generated by immunizing rabbits with PR protein. |
Application Notes | The specificity of the original format of the antibody was confirmed by ELISA analysis (affinity constant of 1.82 × 10^10 M-1). The antibody specifically detected PR protein in Western blot analysis. The antibody 14B3 and the commercial antibody 1E2 were used to stain breast cancer and endometrial. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 14B3 was higher than the commercial antibody (CN113583132A). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
