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Anti-PIVKA-II mAbs

简要描述:

​This antibody is specific for human PIKVA-II.

产品参数:

Cat. No.:MABL-2698

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:in vitro, ELISA

详细介绍

Key features and   details


Cat. No.

MABL-2698

Name

Anti-PIVKA-II mAbs

Clone No.

AFD- PV-Ab1

From

Recombinant Antibody

Isotype

Engineer antibody

Application

in vitro, ELISA

Species Reactivity

Human

Basic Information


Specificity

This antibody is specific for human PIKVA-II.

Alternative Name

Protein induced by vitamin K deficiency-II; protein induced by vitamin K absence-II; abnormal prothrombin glycoprotein

UniProt


Immunogen

The original antibody was generated by   immunizing BALB/c mice with a polypeptide sequence based on the 11th-26th amino   acid sequence of PIVKA-II. This region specifically lacked γ- carboxylation,   which helped distinguish it from normal thrombin. An additional 8 amino acid   sequence was added to enhance immunogenicity. The immunogen was coupled to   KLH using EDC as a crosslinker.

Application Notes

The original antibody's specificity was   validated via an ELISA. This antibody was successfully used as part of a   chemiluminescent detection kit for PIKVA-II, with a detection limit of 1.38   mAU/mL (CN112175925A).

Antibody First   Published


Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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