Key features and details | |
Cat. No. | MABL-2698 |
Name | Anti-PIVKA-II mAbs |
Clone No. | AFD- PV-Ab1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | in vitro, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for human PIKVA-II. |
Alternative Name | Protein induced by vitamin K deficiency-II; protein induced by vitamin K absence-II; abnormal prothrombin glycoprotein |
UniProt | |
Immunogen | The original antibody was generated by immunizing BALB/c mice with a polypeptide sequence based on the 11th-26th amino acid sequence of PIVKA-II. This region specifically lacked γ- carboxylation, which helped distinguish it from normal thrombin. An additional 8 amino acid sequence was added to enhance immunogenicity. The immunogen was coupled to KLH using EDC as a crosslinker. |
Application Notes | The original antibody's specificity was validated via an ELISA. This antibody was successfully used as part of a chemiluminescent detection kit for PIKVA-II, with a detection limit of 1.38 mAU/mL (CN112175925A). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
