Key features and details | |
Cat. No. | MABL-2496 |
Name | Anti-NORE1A mAbs |
Clone No. | AFD- 10F10-C6-C6 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, IF |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody reacts with NORE1A epitope located within amino acids 119-191 of the human NORE1A protein, a unique sequence in the NORE1A splice form. |
Alternative Name | Ras association domain-containing protein 5; New ras effector 1; Regulator for cell adhesion and polarization enriched in lymphoid tissues; RAPL |
UniProt | Q8WWW0 |
Immunogen | The original antibody was generated by immunizing mice against amino acids 119-416 of human NORE1A. |
Application Notes | This antibody has been used to specifically bind NORE1A in Western blots (Kuznetsov et al, 2008; pmid:19098985); it detected NORE1A in human HBEC3-KT cells (Moshnikova et al, 2006; pmid:16421102). Immunofluorescence was performed on human bronchial epithelial cells (HBEC3-KT or HBEC3-KTR) using this antibody (Moshnikova et al, 2006; pmid:16421102). |
Antibody First Published | Moshnikova et al. The growth and tumor suppressor NORE1A is a cytoskeletal protein that suppresses growth by inhibition of the ERK pathway J Biol Chem. 2006 Mar 24;281(12):8143-52. PMID:16421102 |
Note on publication | The article describes the generation and characterization of the antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
