Anti-Myotoxin II mAbs

Cat. No.

MABL-2445

Name

Anti-Myotoxin II mAbs

Clone No.

AFD- TPL0039_05_E2

From

Recombinant Antibody

Isotype

Engineer antibody

Application

plate test

Species Reactivity

Bothrops asper (Terciopelo)

Basic Information

Specificity

TPL0039_05_E2 antibody recognizes   myotoxin-II, which is one of the major toxins in the venom of the snake   Bothrops asper (Terciopelo).

Alternative Name

Basic phospholipase A2 homolog 2; svPLA2   homolog; Myotoxin-II; MtxII

UniProt

P24605

Immunogen

In order to raise the antibody, three phage   display selection rounds were performed against myotoxin-II, using the IONTAS library. The IONTAS library is a human antibody phage display library of 4 x   10^10 clones displaying antibodies in the short chain variable fragment   (scFv) form.

Application Notes

TPL0039_05_E2 scFv (and its other antibody   formats) is recommended for the research on anti-myotoxin-II (Bothrops asper   (Terciopelo)) treatment (for snakebites).

Antibody First   Published

Sørensen et al. Discovery of human   recombinant antibodies against myotoxin-II from the notorious Bothrops asper.   10.13140/RG.2.2.35413.47847.

Note on publication

This poster describes the generation and   characterization of the TPL0039_05_E2 antibody, as a potential treatment for   Bothrops asper snakebites.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.