Anti-MPXV M1R protein mAbs

Cat. No.

MABL-2398

Name

Anti-MPXV M1R protein mAbs

Clone No.

AFD- #40

From

Recombinant Antibody

Isotype

Engineer antibody

Application

neutralize, ELISA

Species Reactivity

Cowpox virus (CPXV), Monkeypox virus (Mpox),   Vaccinia virus (VACV), Variola virus (VARV)

Basic Information

Specificity

This antibody binds the M1R protein of the   monkeypox virus. This antibody also cross reacts with M1R protein vaccinia  virus, variola virus and cowpox virus. . Mpox is an infectious disease caused   by the monkeypox virus which can be transmitted to humans through physical   contact with someone who is infectious, with contaminated materials, or with   infected animals. It can cause a painful rash or mucosal lesions which can   last 2–4 weeks, enlarged lymph nodes and fever. Monkeypox mortality rates range from 0%-11% in the general population and are higher in young children.   In Q3 of 2024, the WHO declared monkeypox a Public Health Emergency of   International Concern. This product serves as a powerful tool for related   research efforts.

Alternative Name

Mpox; MPXV; Monkeypox virus; Monkey pox   virus; MONPV; IMV membrane protein; M1R; MPXV-COP-074; MPXV-SL-074;   MPXV-WRAIR074; MPXVgp080; Myristylprotein

UniProt

Q5IXU5

Immunogen

The original antibody was generated by immunizing   mice with recombinant Mpox M1R protein expressed in mammalian cells.

Application Notes

This antibody is capable of recognizing M1R protein of monkeypox virus, vaccinia virus, variola virus and cowpox virus in   an ELISA. In vitro, this antibody was capable of neutralizing VACV infection   (CN117466994).

Antibody First   Published

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.