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Anti-MPT32 mAbs

简要描述:

This antibody binds the MPT32 protein of Mycobacterium tuberculosis (MTB). MPT32 is a protein encoded by the Mtb Rv1980 gene, is one of the important secretory protein of the pathogenic bacteria, which is a candidate protein for the diagnosis of MTB infections. MPT32 has high immunogenicity and serves as a potent antigen in animals immunized with live bacteria, it induces a strong delayed-type hypersensitivity (DTH) in immunized animals. It mostly elicits a Th1 type of T-cell response in healthy humans; induces IFN-gamma production from CD4+ and CD8+ cells.

产品参数:

Cat. No.:MABL-2396

Species:Engineer

Species Reactivity:Mycobacterium tuberculosis

Type:Recombinate

Application:WB, ELISA

详细介绍

Key features and   details


Cat. No.

MABL-2396

Name

Anti-MPT32 mAbs

Clone No.

AFD- 13B12

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, ELISA

Species Reactivity

Mycobacterium tuberculosis

Basic Information


Specificity

This antibody binds the MPT32 protein of   Mycobacterium tuberculosis (MTB). MPT32 is a protein encoded by the Mtb   Rv1980 gene, is one of the important secretory protein of the pathogenic   bacteria, which is a candidate protein for the diagnosis of MTB infections.   MPT32 has high immunogenicity and serves as a potent antigen in animals   immunized with live bacteria, it induces a strong delayed-type  hypersensitivity (DTH) in immunized animals. It mostly elicits a Th1 type of T-cell response in healthy humans; induces IFN-gamma production from CD4+ and   CD8+ cells.

Alternative Name

MTB MPT32; MPT-32; FAP-B; Rv1860; apa;   Alanine and proline-rich secreted protein Apa; 45 kDa glycoprotein; 45/47 kDa   antigen; Antigen MPT-32; Fibronectin attachment protein; Immunogenic protein   MPT32; modD; MTCY359.13

UniProt

P9WIR7

Immunogen

The original antibody was generated by immunizing mice with recombinant Mycobacterium tuberculosis MPT32 protein.

Application Notes

The binding characterization of this   antibody towards Mycobacterium tuberculosis MPT32 protein was done using   ELISA. This antibody can also recognize MTP32 protein from tuberculosis patient samples in a western blot (CN114591427).

Antibody First   Published


Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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