Anti-Lys–amidine-GM3g mAbs

Cat. No.

MABL-2291

Name

Anti-Lys–amidine-GM3g mAbs

Clone No.

AFD- BAR-1

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ELISA

Species Reactivity

Human

Basic Information

Specificity

This antibody is specific for   Lys–amidine-GM3g.

Alternative Name

ganglioside GM3

UniProt

Immunogen

The original antibody was raised by   immunizing a mouse with HEL-[–X-GM3g]6 LOG antigens.

Application Notes

This antibody was used for an ELISA on   ganglioside GM3. This antibody was used for surface plasmon resonance on   C(NH)NH)-GM3g. The structure of this antibody was determined using x-ray   crystallography (Deimel et al., 2023).

Antibody First   Published

Deimel et al. Engineered display of   ganglioside-sugars on protein elicits a clonally and structurally constrained   B cell response biorxiv

Note on publication

The original paper used protein editing   methods to display GM3g in systematically varied non-native presentation   modes by attachment to carrier protein lysine sidechains using diverse   chemical linkers to probe the limits of glycan tolerance.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.