Key features and details | |
Cat. No. | MABL-2018 |
Name | Anti-IL-10 mAbs |
Clone No. | AFD- AbAb02-IL10 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human IL-10. Interleukin 10 is a major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. |
Alternative Name | IL10; IL10A; B-TCGF; TGIF; Interleukin-10; Interleukin 10; Cytokine synthesis inhibitory factor (CSIF) |
UniProt | P22301 |
Immunogen | The original antibody was generated by immunizing New Zealand white rabbits with recombinant human IL-10 protein. |
Application Notes | The original rabbit IgG antibody binds human IL-10 with a high affinity and has a dissociation constant (Kd) of 9.68×10^(-12) M. A combination of AbAb01-IL10 and AbAb02-IL10 can be used in a double antibody sandwich ELISA, where AbAb01-IL10 is used as a capture antibody and AbAb02-IL10 is used as a detection antibody. The sensitivity of human IL-10 detection for this pair was reported to be 125pg/ml (CN114349858). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
