Key features and details  | |
Cat. No.  | MABL-1951  | 
Name  | Anti-IGF-1 mAbs  | 
Clone No.  | AFD- 7973 (M23)  | 
From  | Recombinant Antibody  | 
Isotype  | Engineer antibody  | 
Application  | WB, IHC  | 
Species Reactivity  | Rat, Human, Mouse  | 
Basic Information  | |
Specificity  | This antibody is specific for IGF-1.  | 
Alternative Name  | CD221; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor  | 
UniProt  | P08069  | 
Immunogen  | The original antibody was raised by immunizing a mouse with IGF-1.  | 
Application Notes  | The original version of this antibody was used for immunohistochemistry on infraorbital nerve tissue. The antibody was able to stain the IGF-1 protein in the tissue (Sugawara et al., 2019; PMID: 31861182). This antibody was used for a western blot on injured or sham-treated infraorbital nerve and trigeminal ganglion (Sugawara et al., 2019; PMID: 31861182), on PC-12 cells (Wang et al., 2021; PMID: 33484421), and on hUCMSCs (Li et al., 2017; PMID: 28279229).  | 
Antibody First Published  | Li et al. Human umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism Stem Cell Res Ther. 2017 Mar 9;8(1):55. PMID:28279229  | 
Note on publication  | The original paper designs an experimental study in order to investigate whether the transplantation of hUCMSCs can improve the ovarian reserve function of perimenopausal rats and delay ovarian senescence.  | 
COA Information (For reference only, actual COA shall prevail)  | |
Size  | 100 μg Purified antibody.  | 
Concentration  | 1 mg/ml.  | 
Purification  | Protein A affinity purified  | 
Buffer  | PBS with 0.02% Proclin 300.  | 
Concentration  | 1 mg/ml.  | 
Storage Recommendation  | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.  | 

  