Key features and details | |
Cat. No. | MABL-1947 |
Name | Anti-IgD mAbs |
Clone No. | AFD- IgD26 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FACS, WB, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody recognises human IgD which is a main antigen receptor on the surface of immature B-cells and small amount of it is secreted to the blood serum. On B-cells it takes part in the activation of these lymphocytes. |
Alternative Name | immunoglobulin D; immunoglobulin heavy constant delta; Igh-5; Ighd; immunoglobulin Delta |
UniProt | P01880 |
Immunogen | This antibody was raised by immunising mice with IgD purified from human myeloma serum. |
Application Notes | IgD26 may be used as a primary or secondary antibody. For instance, one group used anti-IgD antibody to label IgD in a cryostat tonsil section in the immunoperoxidase staining (Naiem et al., 1982). |
Antibody First Published | Taylor and Mason The immunohistological detection of intracellular immunoglobulin in formalin-paraffin sections from multiple myeloma and related conditions using the immunoperoxidase technique. Clin Exp Immunol. 1974 Nov;18(3):417-29. PMID:4219910 |
Note on publication | This article describes the earliest application of this antibody present in the literature. The more detailed desription of the generation of such antibodies is described in the following paper: Naiem, M., Gerdes, J., Abdulaziz, Z., Sunderland, C. A., Allington, M. J., Stein, H., & Mason, D. Y. (1982). The value of immunohistological screening in the production of monoclonal antibodies. Journal of immunological methods, 50(2), 145-160. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
