Anti-IgD mAbs

Cat. No.

MABL-1947

Name

Anti-IgD mAbs

Clone No.

AFD- IgD26

From

Recombinant Antibody

Isotype

Engineer antibody

Application

FACS, WB, IHC

Species Reactivity

Human

Basic Information

Specificity

This antibody recognises human IgD which is   a main antigen receptor on the surface of immature B-cells and small amount   of it is secreted to the blood serum. On B-cells it takes part in the   activation of these lymphocytes.

Alternative Name

immunoglobulin D; immunoglobulin heavy   constant delta; Igh-5; Ighd; immunoglobulin Delta

UniProt

P01880

Immunogen

This antibody was raised by immunising mice with IgD purified from human myeloma serum.

Application Notes

IgD26 may be used as a primary or secondary antibody. For instance, one group used anti-IgD antibody to label IgD in a   cryostat tonsil section in the immunoperoxidase staining (Naiem et al.,   1982).

Antibody First   Published

Taylor and Mason The immunohistological   detection of intracellular immunoglobulin in formalin-paraffin sections from   multiple myeloma and related conditions using the immunoperoxidase technique.   Clin Exp Immunol. 1974 Nov;18(3):417-29. PMID:4219910

Note on publication

This article describes the earliest  application of this antibody present in the literature. The more detailed   desription of the generation of such antibodies is described in the following   paper: Naiem, M., Gerdes, J., Abdulaziz, Z., Sunderland, C. A., Allington, M.   J., Stein, H., & Mason, D. Y. (1982). The value of immunohistological   screening in the production of monoclonal antibodies. Journal of   immunological methods, 50(2), 145-160.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.