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Anti-IFN gamma mAbs

简要描述:

Binds human interferon-gamma, a dimerized soluble cytokine that is the only member of the type II class of interferons. Cross reacts with baboon IFN gamma.

产品参数:

Cat. No.:MABL-1933

Species:Engineer

Species Reactivity:Baboon, Human

详细介绍

Key features and   details


Cat. No.

MABL-1933

Name

Anti-IFN gamma mAbs

Clone No.

AFD- D9D10

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, Block, ELISA, FC

Species Reactivity

Baboon, Human

Basic Information


Specificity

Binds human interferon-gamma, a dimerized soluble cytokine that is the only member of the type II class of interferons.   Cross reacts with baboon IFN gamma.

Alternative Name

Interferon gamma; Immune interferon; IFN-gamma; IFNG

UniProt

P01579

Immunogen

FPLC-purified natural human IFN-y. Refer to the original article [PMID: 3114127]

Application Notes

This antibody can be used to detect both native and recombinant intereferon gamma (IFNg). It is reported only to bind   to the functional, dimeric form of IFNg.

Antibody First   Published

Froyen G, Ronsse I, Billiau A. Bacterial   expression of a single-chain antibody fragment (SCFV) that neutralizes the   biological activity of human interferon-gamma. Mol Immunol. 1993   Jun;30(9):805-12. PMID:8321246

Note on publication

Describes the preparation anti human interferon   gamma antibody by D9D10 hybridoma seqencing (VH and VK) and identified using   ELISA and SDS-PAGE (for neuralisation of antiviral activity) techniques.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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